KIF2C anticorps (AA 550-600)

N° du produit ABIN7451556

Cet anticorps anti-KIF2C est un anticorps Lapin Polyclonal détectant KIF2C dans IP. Adapté pour Souris.

Aperçu rapide pour KIF2C anticorps (AA 550-600) (ABIN7451556)

Antigène: KIF2C (Kinesin Family Member 2C (KIF2C))

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KIF2C est non-conjugé

Application: Immunoprecipitation (IP)

Détail du produit anti-KIF2C anticorps

Épitope: AA 550-600

Fonction: Rabbit anti-MCAK Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: between AA 550 and 600

Isotype: IgG

Information d'application

Indications d'application:

IP: 2 - 5 μg/mg lysate. is less efficient at IP than is ABIN7451556.

WB: Not recommended. Use rabbit anti-MCAK antibody .

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur KIF2C

Antigène: KIF2C (Kinesin Family Member 2C (KIF2C))

Autre désignation: MCAK

Sujet: Background: Kinesin activity has been linked to various cellular functions such as vesicle transport, mitotic spindle formation, chromosome segregation, chromosome congression, and cytokinesis. Structurally, all kinesins contain a motor domain with microtubule and nucleotide binding sites that utilize ATP to target cargo along microtubule filaments. MCAK (Mitotic Centromere-Associated Kinesin) is the founding member of kinesin-13 proteins. There are 3 independent genes coding for kinesin-13 proteins kif2a, kif2b, and kif2c (MCAK). Instead of functioning as a translocator of microtubules MCAK is a depolymerizer that is primarily responsible for releasing improper microtubule-kinetochore attachments during cell division.

ID gène: 73804

NCBI Accession: NP_608301

UniProt: Q922S8

Pathways: Dynamique des Microtubules